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Do you think that the level of Flavonols in our food now is the same as it may have been a long time ago? I wonder given that a lot of our produce now a days is low in the nutrients that they are toted as carrying. But I don't understand chemistry so I have no idea if Flavonols would be impacted by this.

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I would suspect so tbh. The soil also affects the quality of the produce, so considering a lot is over harvested based on modern agriculture it would make sense. I'm not sure by how much less each nutrient is, might be an interesting topic to delve more into, but I speculate it would vary by region, the way the plants are grown, the chemicals used on them and more...

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That's what I was wondering as well. This is something my fiancé and I talk a lot about. We really want to be able to grow our own food.

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Your article brought me down the internet rabbit hole, lol. I'd volunteer for the cocoa extract study! So, I then had to read the study. Then, I had to find the company of the product they used in the study. And, that's how I landed on the CocoaVia website.

Interestingly, they do mention that their product was used in the study, but they fail to mention that the improvement was only seen in the group that was already low on flavonols - which you so eloquently mentioned in your article. Marketing! I'm sure that drives you nuts as a medical scientist.

Out of curiosity and the 597 5-star reviews for the product, I may try it. I'm not a big supplement person as I try to get my nutrients from food, but now I'm really curious.

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It’s so frustrating, but this is also seen in non-industry funded studies as the notion of publishing is only if a statistical p value is shown, and hence all the group comparisons. Which in part makes sense just like comparing high vs low alcohol consumption but still hard to translate clinically. The group comparison was probably mentioned in the tiniest footnote under some hidden location 😅

I completely agree re supplements, with the exception of vit D, unless deficient in something truly not much need to supplement. Even harm could be caused. Let’s not forget that the supplement industry is not properly regulated - but then this opens another argument re the FDA, EFSA etc

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I'm picking up on what you're putting down—we'll have to meet sometime. You know the inside story, and you know what's real and what's not, and hopefully, that helps you sleep better at night than the others who manipulate information. You'd go nuts learning about what's happening in the supplement world for perimenopause and menopausal women. It's truly disturbing. We'll stick together - there is strength in numbers. Keep up the great job!

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I wouldn’t be surprised tbh! I’ve seen an array of supplements promising to “cure” an array symptoms or somehow aiming to mimic hormone therapy. However, that being said I do suspect a lot of their improvements are indeed placebo, our brain is much more powerful that we think!

Would love to connect further, and learn more about your findings!

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Yet another reason I am so glad I love fruits and veggies (and tea)! Thanks for the great piece 😊

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Thank you, Preston! Happy to hear you enjoyed it :)

I could solely live off fruit, especially those of the summer-season!

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